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Found 340 results
  1. Content Article
    Polypharmacy is a term used to describe when a patient is taking a number of medicines at the same time. This study in the British Journal of Clinical Pharmacology aimed to measure how common polypharmacy is and describe the prescribing of selected medications known for overuse in older people with polypharmacy in primary care. It was a multinational retrospective cohort study that used data from patients with a mean age of 75-76 years from six countries: Belgium, France, Germany, Italy, Spain and the UK. The results revealed a high prevalence of polypharmacy with more than half of the older population being prescribed at least five drugs in four of the six countries. Whilst polypharmacy may be appropriate in many patients, the authors found worryingly high usage of PPIs and benzodiazepines. The study's results support current efforts to improve polypharmacy management across Europe.
  2. Content Article
    Medicines reconciliation is the process of compiling a complete list of a person’s current medicines. When a patient registers at a new primary care setting, medicines reconciliation contributes to patient safety and continuity of care. This article in The Pharmaceutical Journal explores how to optimise the multidisciplinary team and involve pharmacy technicians in the process, using four case scenarios. The article aims to help those working in community pharmacy teams to: identify potential risks and appropriate management strategies for new patients with complex medication needs, including those with chronic conditions and those requiring specialist care. understand the importance of timely referrals, communication with specialists, and adherence to guidelines in ensuring safe and effective medication management. recognise the significance of interdisciplinary collaboration and patient-centred approaches in addressing the diverse healthcare needs of patients, particularly those from other cultural backgrounds. You can access this article by signing up for a free account with The Pharmaceutical Journal.
  3. Event
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    Medication errors are a leading cause of injury and avoidable harm in healthcare, with an estimated 1.3 million people impacted in the U.S. each year. Preventable medication errors cost the nation more than $21 billion annually across all care settings, representing a serious public health concern, as well as an economic burden on our healthcare system. Join AHRQ’s expert panel of speakers to hear how quality improvement approaches and digital healthcare interventions such as clinical decision support tools are reducing medication errors, improving provider effectiveness, and enhancing patient safety in a variety of clinical care settings. At the conclusion of this Webinar, participants should be able to: Discuss how an e-prescribing tool can reduce medication discrepancies and improve patient safety by enhancing communication between pharmacists and providers. Identify how clinical decision support systems can significantly reduce the prescribing of potentially inappropriate medications to older patients at the time of discharge from the emergency department setting. Explain how outcome measures, such as the Wrong-Patient Retract-and-Reorder measure, can be developed and used to detect medication errors in electronic orders. Register
  4. News Article
    Young women are ending up in A&E after buying Ozempic online, with the NHS’s top doctor warning that weight-loss injections should not be abused in an attempt to get “beach body ready”. Doctors in emergency care report that “almost every shift” they see “young, beautiful girls” with potentially deadly complications who took the drug despite being a healthy weight. New weight-loss injections including semaglutide, better known by the brand names Ozempic and Wegovy, are being used on the NHS for people with obesity and type 2 diabetes. Some patients, however, including those with eating disorders, have lied about their weight to get them privately from online pharmacies or beauty clinics — leading to complications including inflammation of the pancreas. The drugs are sold by companies including Boots, Superdrug and Lloyds at between £150 and £200 a month. Doctors are calling for “urgent regulation and control” of their sale to ensure they are prescribed only to obese patients. Professor Stephen Powis, NHS England’s medical director, said the drugs should not be seen as a “quick fix for people trying to get ‘beach body ready’ ”. Read full story (paywalled) Source: The Times, 13 June 2024
  5. News Article
    Almost half of adults in the UK have struggled to get medicine they have been prescribed – and more people blame Brexit than anything else for the situation, research shows. Forty-nine per cent of people said they had had trouble getting a prescription dispensed over the past two years, the period during which supply problems have increased sharply. Drug shortages are so serious that 1 in 12 Britons were unable to find the medication they needed, despite asking a number of pharmacies. The survey of 2,028 people representative of the population, undertaken by Opinium for the British Generic Manufacturers Association (BGMA), found that: One in 12 people (8%) have gone without a medication altogether because it was impossible to obtain. Thirty-one per cent found the drug they needed was out of stock at their pharmacy. Twenty-three per cent of pharmacies did not have enough of the medication available. “Shortages are deeply worrying for patients’ physical health, alongside the stress of not knowing if an essential medicine will be available,” said Mark Samuels, the chief executive of the BGMA. Read full story Source: The Guardian, 16 June 2024
  6. Content Article
    This full-length, award-winning documentary unearths the shattering truth that millions of people worldwide are injured by prescribed psychiatric medications. Interweaving stories of harm with expert testimony, the film reveals how a profit-driven industry hides the risks of long-term use. This untold story is a compelling call to examine the consequences of medicating normal human suffering.
  7. Content Article
    This blog is part of a series written by Dr Charlie*, taking a closer look at some of the patient safety issues affecting people lives today. In this blog Dr Charlie tells us how their elderly mother was met with multiple digital barriers when trying to access her medications. Describing the situation as a frustrating goose-chase, Dr Charlie summarises the blog by questioning what measures are put in place to safeguard patients during digital transformations.  *not the authors real name
  8. Content Article
    Safety-netting advice is information shared with a patient or their carer to help them identify the need to seek further help if their condition fails to improve or changes. In some instances, it is mandatory for pharmacists to give patients safety-netting advice. This article in the Pharmaceutical Journal provides advice for pharmacists on how they can provide this advice clearly and appropriately. The article explains the importance of safety-netting and when it is appropriate, describes elements to include when safety-netting and provides advice on how to adequately document advice given.
  9. Content Article
    This US cross-sectional study in JAMA Network Open aimed to find out whether there is a difference in reported inappropriate antipsychotic medication use between severely and less severely deprived neighbourhoods, and whether this difference is modified by greater total nurse staffing hours. The study included 10,966 nursing homes and found that nursing homes that fell below critical levels of staffing (less than three hours of nurse staffing per resident-day), were associated with higher inappropriate antipsychotic medication use among nursing homes in severely deprived neighbourhoods (19.2%) compared with nursing homes in less deprived neighbourhoods (17.1%). These findings suggest that addressing staffing deficiencies in nursing homes, particularly those located in severely deprived neighbourhoods, is crucial in mitigating inappropriate antipsychotic medication use.
  10. News Article
    For the past 16 years, I have run a small community pharmacy in rural west Dorset. My business is older than me – the little yellow-brick building I own is about to turn 235. Right now, I am really concerned about it getting through the next 12 months. In my years as a pharmacist, I have never seen things as bad as they are at the moment. We are going through a period of rampant drug shortages in England, caused by global shortages, the NHS’s insistence on paying unsustainably low prices for medicines and Brexit, among other things, and people are on the brink. Long gone are the days when customers could place a prescription order safe in the knowledge their life-saving medication would arrive the next day. Read full story Source: Guardian, 17 May 2024
  11. News Article
    Pharmacists are calling for fresh powers to provide patients with alternative prescriptions as they warned that drugs shortages are hampering their ability to tackle whooping cough. More than 2,700 cases have been reported across England so far in 2024 – more than three times the number recorded in the whole of last year. But some pharmacies have been forced to turn away families seeking help for their children because they have run out of clarithromycin, a key antibiotic used to treat the condition. Read full story Source: Guardian, 20 May 2024
  12. Content Article
    Pharmacies in the UK dispense millions of prescription items each year. Since 2021 there have been reports of increasing supply problems affecting medicines. Recent media coverage has highlighted shortages of medicines used to treat diabetes, attention deficit hyperactivity disorder (ADHD) and epilepsy, as well as hormone replacement therapy (HRT) and others. This briefing provides information on the causes and consequences of medicines shortages in the UK and internationally, and the UK Government’s approach to address supply problems.
  13. Content Article
    Antimicrobial resistance (AMR) occurs when bacteria, and other microorganisms, develop resistance to antimicrobial drugs, such as antibiotics, making them less responsive or unresponsive to treatment. This National Action Plan sets out how the UK will reduce its use of antimicrobials in humans and animals, strengthen surveillance of drug resistant infections before they emerge and incentivise industry to develop the next generation of treatments.
  14. Content Article
    Despite widespread efforts to combat the opioid epidemic, post-operative opioid overprescribing by doctors remains an ongoing contributor to opioid misuse. This US study aimed to evaluate the impact of a low-cost, reproducible “just in time” intervention on opioid prescribing in dialysis access operations. Standardised opioid prescribing guidelines were emailed to residents on the vascular service on the first day of the rotation. Opioid prescriptions were reviewed for four years before and one year after this intervention. The results showed a decrease in patients discharged with opioids following the intervention, from 58% to 36%. For patients prescribed opioids, the median quantity decreased from 90 to 45 oral morphine equivalents.
  15. News Article
    A man who suffered a psychotic episode which lasted for weeks was not fully informed about potential extreme side-effects of taking steroids medication, England’s health service Ombudsman has found. Andrew Holland was prescribed steroids in early January 2022 by Manchester Royal Eye Hospital after losing vision in his left eye and suffering a severe infection in his right eye. The 61-year-old from Manchester was given the medication as treatment for eye inflammation, but soon began suffering from disrupted sleep and severe headaches. These side-effects developed into more serious ones, including becoming aggressive, psychotic, and inexplicably wandering the street at different times of the day and night. After several hospital visits due to his symptoms, Andrew attended Manchester University NHS Foundation Trust’s emergency department in mid-January with a severe headache and later became an inpatient. He was diagnosed with steroid induced psychosis, with symptoms including hallucinations, insomnia and behaviour changes. Though no failings were found with Manchester University NHS Foundation Trust in prescribing Andrew with steroids for the eye condition, the Ombudsman discovered a missed opportunity to fully inform him of potential extreme side-effects. He was therefore unable to make a fully informed decision about whether to take them or not. The Trust apologised for an ‘unsatisfactory experience’. However, the Ombudsman found relevant guidelines were not followed. Moreover, there had been no acknowledgement of mistakes in communication about the side-effects. Nor was any attempt made to correct them. Read full story Source: PSHO, 10 April 2024
  16. Content Article
    Clinical guidelines can contribute to medication errors but there is no overall understanding of how and where these occur. This study aimed to identify guideline-related medication errors reported via a national incident reporting system, and describe types of error, stages of medication use, guidelines, drugs, specialties and clinical locations most commonly associated with such errors.
  17. News Article
    Drugs are a cornerstone of medicine, but sometimes doctors make mistakes when prescribing them and patients don’t take them properly. A new AI tool developed at Oxford University aims to tackle both those problems. DrugGPT offers a safety net for clinicians when they prescribe medicines and gives them information that may help their patients better understand why and how to take them. Doctors and other healthcare professionals who prescribe medicines will be able to get an instant second opinion by entering a patient’s conditions into the chatbot. Prototype versions respond with a list of recommended drugs and flag up possible adverse effects and drug-drug interactions. “One of the great things is that it then explains why,” said Prof David Clifton, whose team at Oxford’s AI for Healthcare lab led the project. “It will show you the guidance – the research, flowcharts and references – and why it recommends this particular drug.” Read full story Source: The Guardian, 31 March 2024
  18. Content Article
    Harm due to medicines and therapeutic options accounts for nearly 50% of preventable harm in medical care. This World Health Organization (WHO) policy brief is a resource for policy-makers, health workers, healthcare leaders, academic institutions and other relevant institutions to help understand the global burden of medication errors, address and prevent medication-related harm at all levels of healthcare, aligned with the strategic plan of the third WHO Global Patient Safety Challenge: Medication Without Harm. 
  19. Content Article
    Medication errors in ambulatory care settings present unique patient safety challenges. This systematic review explored the prevalence of medication errors in outpatient and ambulatory care settings. Findings indicate that prescribing errors (e.g., dosing errors) are the most common type of medication error and are often attributed to latent factors, such as knowledge gaps.
  20. News Article
    Children will no longer routinely be prescribed puberty blockers at gender identity clinics, NHS England has confirmed. The decision comes after a review found there was "not enough evidence" they are safe or effective. Puberty blockers, which pause the physical changes of puberty, will now only be available as part of research. It comes weeks before an independent review into gender identity services in England is due to be published. An interim report from the review, published in 2022 by Dr Hilary Cass, had earlier found there were "gaps in evidence" around the drugs and called for a transformation in the model of care for children with gender-related distress. Health Minister Maria Caulfield said: "We have always been clear that children's safety and wellbeing is paramount, so we welcome this landmark decision by the NHS. "Ending the routine prescription of puberty blockers will help ensure that care is based on evidence, expert clinical opinion and is in the best interests of the child." Read full story Source: BBC News, 13 March 2024
  21. Content Article
    In this interview, we talk to Darren Powell, Clinical Lead for NHS England and Community Pharmacist, about medication supply issues. Darren shares his experiences of how medication shortages and tariffs are affecting patients and staff and offers insights into the complexity of the situation.  He tells us his thoughts on potential causes and barriers, as well as suggesting three actions for wider system safety. 
  22. Content Article
    This study aimed to determine whether the use of video telemedicine for paediatric consultations to referring hospital emergency departments (EDs) results in less frequent medication errors than the current standard of care—telephone consultations. The authors found no statistically significant differences in physician-related medication errors between children assigned to receive telephone consultations vs video telemedicine consultations.
  23. Content Article
    This article in the Pharmaceutical Journal outlines best practice principles and practical advice for structuring antimicrobial reviews and effective stewardship practices. It aims to equip pharmacists to: Understand the role of essential antimicrobial stewardship tools and frameworks to improve antibiotic prescribing; Structure an antimicrobial review effectively, covering all relevant details; Personalise the antimicrobial review to ensure patient-centred care and effective antimicrobial stewardship practices; Develop skills for effective antimicrobial review and stewardship practices to mitigate antimicrobial resistance threat.
  24. Content Article
    This consensus statement co-ordinated by the British In Vitro Diagnostics Association (BIVDA) outlines the role of point of care testing in reducing the amount of antibiotics prescribed in primary care. It highlights the issue of antimicrobial resistance (AMR) and outlines evidence for the effectiveness of the rapid point-of-care C-Reactive Protein (POC CRP) test to assist clinical decision making as to whether an individual presenting with symptoms of respiratory tract infection needs an antibiotic. It makes a series of recommendations for the Department of Health and Social Care (DHSC) and NHS England around the use of POC CRP testing in primary care.
  25. Content Article
    Salbutamol is a selective beta2-agonist providing short-acting (4-6 hour) bronchodilation with a fast onset (within 5 minutes) in reversible airways obstruction. The nebuliser liquids are licensed for use in the management of chronic bronchospasm unresponsive to conventional therapy, and in the treatment of acute severe asthma. A Medicines Supply Notification (MSN) issued on 14 February 2024, detailed a shortage of salbutamol 2.5mg/2.5ml and 5mg/2.5ml nebuliser liquid. The resolution date is to be confirmed. The supply issues have been caused by a combination of manufacturing issues resulting in increased demand on other suppliers. Terbutaline, salbutamol with ipratropium, and ipratropium nebuliser liquids remain available, however, they cannot support an increase in demand. Ventolin® (salbutamol) 5mg/ml nebuliser liquid (20ml) is out of stock until mid-April 2024 and cannot support an increased demand after this date.
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